[Home ]     [ فارسي ]  
Archives of Razi awt-yekta نشريه علمى - پژوهشى آرشيو رازي
:: Main :: Current Issue :: Archive :: Search :: Submit ::
:: Volume 60, Number 1 (4-2005) ::
Back to browse issues page 3 2005, 60(1): 21-32
XML Evaluation the Efficacy of Anthrax Vaccine against Challenge with a Highly Virulent Strain of Bacillus Anthracis Isolated from Soil in Sheep, Goats and Guinea Pigs in Iran Print

Author(s): G. Moazeni Jula * , A.R. Jabbari
Study Type: Full Article | Subject: Veterinary Bacteriology
Article abstract:

  Protection of animals immunized against Bacillus anthracis is usually demonstrated by challenging with an appropriate dose of a strain of Bacillus anthracis that is lethal to unvaccinated animals inoculated at the same time. In this study the protective efficacy in anthrax vaccine (34F2 sterne strain spore) was evaluated in sheep, goats and guinea pigs challenged with subcutaneous inoculation of a highly virulent Bacillus anthracis spores recently isolated from soil in Iran. This strain has been shown that it is lethal for sheep, goats and guinea pigs in very low dose. It was found that the vaccine provides highly protection (100 % ) after challenging the immunized animals against this strain in sheep, goats and guinea pigs. So, indicates the superior protective efficacy of the vaccine. The authors recommend that this strain can be used instead of other strain which has been used previously for challenging the immunized animals, and also guinea pig is a good substitution for evaluating anthrax vaccine.

 

KeywordsEfficacy, Anthrax vaccine, Challenge, Sheep, Goat, Guinea pig,
Full text [PDF 137 kb]
How to cite this article
Download citation data for: BibTeX | EndNote | Medlars | ProCite | Reference Manager | RefWorks |  
Send citation data to: CiteULike | RefWorks |
Moazeni Jula G, Jabbari A. Evaluation the Efficacy of Anthrax Vaccine against Challenge with a Highly Virulent Strain of Bacillus Anthracis Isolated from Soil in Sheep, Goats and Guinea Pigs in Iran. 3. 2005; 60 (1) :21-32
URL http://www.archrazi.com/browse.php?a_code=A-10-1-36&slc_lang=en&sid=1
Add your comments about this article
Your username or email:

Write the security code in the box >
 
Back to browse issues page Volume 60, Number 1 (4-2005)
نشريه علمى - پژوهشى آرشيو رازي Archives of Razi
Static site map - Persian site map - English site map - Created in 0.05 seconds with 655 queries by AWT YEKTAWEB 2546